Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Foxa2  forkhead box A2   (Synonyms: Hnf3b, Hnf-3b, HNF3beta, HNF3-beta, Tcf3b, Tcf-3b)
Results	Reference
1*	J:16244 Ang SL, Wierda A, Wong D, Stevens KA, Cascio S, Rossant J, Zaret KS, The formation and maintenance of the definitive endoderm lineage in the mouse: involvement of HNF3/forkhead proteins. Development. 1993 Dec;119(4):1301-15
1*	J:79514 Burke Z, Oliver G, Prox1 is an early specific marker for the developing liver and pancreas in the mammalian foregut endoderm. Mech Dev. 2002 Oct;118(1-2):147
1*	J:79027 Caspary T, Garcia-Garcia MJ, Huangfu D, Eggenschwiler JT, Wyler MR, Rakeman AS, Alcorn HL, Anderson KV, Mouse dispatched homolog1 is required for long-range, but not juxtacrine, Hh signaling. Curr Biol. 2002 Sep 17;12(18):1628-32
1*	J:53293 Chang H, Huylebroeck D, Verschueren K, Guo Q, Matzuk MM, Zwijsen A, Smad5 knockout mice die at mid-gestation due to multiple embryonic and extraembryonic defects. Development. 1999 Apr;126(8):1631-42
1*	J:80954 Chapman DL, Papaioannou VE, Three neural tubes in mouse embryos with mutations in the T-box gene Tbx6. Nature. 1998 Feb 12;391(6668):695-7
1	J:294824 Dias A, Lozovska A, Wymeersch FJ, Novoa A, Binagui-Casas A, Sobral D, Martins GG, Wilson V, Mallo M, A Tgfbr1/Snai1-dependent developmental module at the core of vertebrate axial elongation. Elife. 2020 Jun 29;9:e56615
1*	J:252091 Dzama MM, Nigmatullina L, Sayols S, Kreim N, Soshnikova N, Distinct populations of embryonic epithelial progenitors generate Lgr5(+) intestinal stem cells. Dev Biol. 2017 Dec 15;432(2):258-264
1*	J:16386 Echelard Y, Epstein DJ, St-Jacques B, Shen L, Mohler J, McMahon JA, McMahon AP, Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity. Cell. 1993 Dec 31;75(7):1417-30
1	J:153098 Goss AM, Tian Y, Tsukiyama T, Cohen ED, Zhou D, Lu MM, Yamaguchi TP, Morrisey EE, Wnt2/2b and beta-catenin signaling are necessary and sufficient to specify lung progenitors in the foregut. Dev Cell. 2009 Aug;17(2):290-8
1*	J:119664 Houde C, Dickinson RJ, Houtzager VM, Cullum R, Montpetit R, Metzler M, Simpson EM, Roy S, Hayden MR, Hoodless PA, Nicholson DW, Hippi is essential for node cilia assembly and Sonic hedgehog signaling. Dev Biol. 2006 Dec 15;300(2):523-33
1	J:93588 Hu T, Yamagishi H, Maeda J, McAnally J, Yamagishi C, Srivastava D, Tbx1 regulates fibroblast growth factors in the anterior heart field through a reinforcing autoregulatory loop involving forkhead transcription factors. Development. 2004 Nov;131(21):5491-502
1*	J:106931 Isono K, Nemoto K, Li Y, Takada Y, Suzuki R, Katsuki M, Nakagawara A, Koseki H, Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals. Mol Cell Biol. 2006 Apr;26(7):2758-71
1	J:101263 Ivins S, Lammerts van Beuren K, Roberts C, James C, Lindsay E, Baldini A, Ataliotis P, Scambler PJ, Microarray analysis detects differentially expressed genes in the pharyngeal region of mice lacking Tbx1. Dev Biol. 2005 Sep 15;285(2):554-69
1	J:315774 Junker JP, Peterson KA, Nishi Y, Mao J, McMahon AP, van Oudenaarden A, A predictive model of bifunctional transcription factor signaling during embryonic tissue patterning. Dev Cell. 2014 Nov 24;31(4):448-60
1*	J:75946 Kanai-Azuma M, Kanai Y, Gad JM, Tajima Y, Taya C, Kurohmaru M, Sanai Y, Yonekawa H, Yazaki K, Tam PP, Hayashi Y, Depletion of definitive gut endoderm in Sox17-null mutant mice. Development. 2002 May;129(10):2367-79
1*	J:79831 Kawakami T, Kawcak T, Li YJ, Zhang W, Hu Y, Chuang PT, Mouse dispatched mutants fail to distribute hedgehog proteins and are defective in hedgehog signaling. Development. 2002 Dec;129(24):5753-65
1*	J:41684 Lee J, Platt KA, Censullo P, Ruiz i Altaba A, Gli1 is a target of Sonic hedgehog that induces ventral neural tube development. Development. 1997 Jul;124(13):2537-52
1	J:139252 Lokmane L, Haumaitre C, Garcia-Villalba P, Anselme I, Schneider-Maunoury S, Cereghini S, Crucial role of vHNF1 in vertebrate hepatic specification. Development. 2008 Aug;135(16):2777-86
1	J:62027 Martinez Barbera JP, Clements M, Thomas P, Rodriguez T, Meloy D, Kioussis D, Beddington RS, The homeobox gene Hex is required in definitive endodermal tissues for normal forebrain, liver and thyroid formation. Development. 2000 Jun;127(11):2433-45
1*	J:15715 Monaghan AP, Kaestner KH, Grau E, Schutz G, Postimplantation expression patterns indicate a role for the mouse forkhead/HNF-3 alpha, beta and gamma genes in determination of the definitive endoderm, chordamesoderm and neuroectoderm. Development. 1993 Nov;119(3):567-78
1	J:289632 Nagai MH, Xavier VPS, Gutiyama LM, Machado CF, Reis AH, Donnard ER, Galante PAF, Abreu JG, Festuccia WT, Malnic B, Depletion of Ric-8B leads to reduced mTORC2 activity. PLoS Genet. 2020 May;16(5):e1008255
1*	J:45679 Peterson RS, Lim L, Ye H, Zhou H, Overdier DG, Costa RH, The winged helix transcriptional activator HFH-8 is expressed in the mesoderm of the primitive streak stage of mouse embryos and its cellular derivatives. Mech Dev. 1997 Dec;69(1-2):53-69
1	J:165741 Rojas A, Schachterle W, Xu SM, Martin F, Black BL, Direct transcriptional regulation of Gata4 during early endoderm specification is controlled by FoxA2 binding to an intronic enhancer. Dev Biol. 2010 Oct 15;346(2):346-55
1	J:342640 Sampath Kumar A, Tian L, Bolondi A, Hernandez AA, Stickels R, Kretzmer H, Murray E, Wittler L, Walther M, Barakat G, Haut L, Elkabetz Y, Macosko EZ, Guignard L, Chen F, Meissner A, Spatiotemporal transcriptomic maps of whole mouse embryos at the onset of organogenesis. Nat Genet. 2023 Jul;55(7):1176-1185
1*	J:40390 Sasaki H, Hui C, Nakafuku M, Kondoh H, A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro. Development. 1997 Apr;124(7):1313-22
1	J:166526 Shum AS, Tang LS, Copp AJ, Roelink H, Lack of motor neuron differentiation is an intrinsic property of the mouse secondary neural tube. Dev Dyn. 2010 Dec;239(12):3192-203
1	J:284174 Swarr DT, Herriges M, Li S, Morley M, Fernandes S, Sridharan A, Zhou S, Garcia BA, Stewart K, Morrisey EE, The long noncoding RNA Falcor regulates Foxa2 expression to maintain lung epithelial homeostasis and promote regeneration. Genes Dev. 2019 Jun 1;33(11-12):656-668
1*	J:132031 Wong RL, Wlodarczyk BJ, Min KS, Scott ML, Kartiko S, Yu W, Merriweather MY, Vogel P, Zambrowicz BP, Finnell RH, Mouse Fkbp8 activity is required to inhibit cell death and establish dorso-ventral patterning in the posterior neural tube. Hum Mol Genet. 2008 Feb 15;17(4):587-601
1	J:81296 Yamagishi H, Maeda J, Hu T, McAnally J, Conway SJ, Kume T, Meyers EN, Yamagishi C, Srivastava D, Tbx1 is regulated by tissue-specific forkhead proteins through a common Sonic hedgehog-responsive enhancer. Genes Dev. 2003 Jan 15;17(2):269-81
1	J:87046 Zoltewicz JS, Stewart NJ, Leung R, Peterson AS, Atrophin 2 recruits histone deacetylase and is required for the function of multiple signaling centers during mouse embryogenesis. Development. 2004 Jan;131(1):3-14